TABLE 1.
Reported translatable circRNAs.
| CircRNAs | Proteins | Found in | Mechanism | References |
|---|---|---|---|---|
| Viral curcRNA_000048 | Micropeptide vsp21 | Bombyx mori cypovirus | IRES in a cap-independent manner | Zhang et al. (2022) |
| Circ-E-Cad | C-E-Cad-254aa | Glioblastoma | IRES in a cap-independent manner | Gao et al. (2021) |
| CircHNRNPU | CircHNRNPU-603aa | Mutiple myeloma | IRES in a cap-independent manner | Tang et al. (2022) |
| CircMAPK1 | MAPK1-109aa | Gastric cancer | IRES in a cap-independent manner | Jiang et al. (2021) |
| Circ-SMO | SMO-193aa | Glioblastoma | IRES in a cap-independent manner | Wu et al. (2021) |
| CircDIDO1 | DIDO1-529aa | Gastric cancer | IRES in a cap-independent manner | Zhang Y. et al. (2021) |
| Hsa_circ_0006401 | Hsa_circ_0006401 peptide-198aa | Colorectal cancer | IRES in a cap-independent manner | Zhang C. J. et al. (2021) |
| CircHER2 | HER2-103aa | Triple negative breast cancer | IRES in a cap-independent manner | Li et al. (2020a) |
| CircAβ-a | Aβ175 | Alzheimer’s disease | IRES in a cap-independent manner | Mo et al. (2020) |
| Circ-AKT3 | AKT3-174aa | Gliobastoma | IRES in a cap-independent manner | Xia et al. (2019) |
| CircPPP1R12A | PPP1R12A-73aa | Colon cancer | IRES in a cap-independent manner | Zheng et al. (2019) |
| Circ-SHPRH | SHPRH-146aa | Gliobastoma | IRES in a cap-independent manner | Zhang et al. (2018a) |
| CircPINTexon2 | PINT-87aa | Gliobastoma | IRES in a cap-independent manner | Zhang et al. (2018b) |
| Circ-ZNF609 | ZNF609-250aa | Myogenesis | IRES in a cap-independent manner | Legnini et al. (2017) |
| Circβ-catenin | β-catenin isoform-370 aa | Hepatocellular carcinoma | IRES in a cap-independent manner | Liang et al. (2019) |
| CircMbl1 | Circ-Mbl1-encoded protein | Fly head | IRES in a cap-independent manner | Pamudurti et al. (2017) |
| Circ-FBXW7 | FBXW7-185aa | Gliobastoma | IRES in a cap-independent manner | Yang et al. (2018) |
| CircMbl3 | Circ-Mbl3-encoded protein | Fly head | IRES in a cap-independent manner | Pamudurti et al. (2017) |
| CircE7 | E7 protein | High-risk HPV | m6A-dependent initiation of translation | Zhao et al. (2019) |
| CircARHGAP35 | CircARHGAP35-encoded protein | Hepatocellular carcinoma | m6A-dependent initiation of translation | Li Y. et al. (2021) |
| CircMET | MET404 | Glioblastoma | m6A-dependent initiation of translation | Zhong et al. (2022) |
| Circ-EGFR | Rolling-translated-EGFR | Glioblastoma | Rolling circle translation | Liu Y. et al. (2021) |
| 50% of translatable endogenous circRNAs | NA | 293T | Rolling circle translation | Fan et al. (2022) |
| CircSfl | CircSfl-encoded peptide | Fly brain and muscle | NA | Weigelt et al. (2020) |
| CircGprc5a | CircGprc5a-peptide | Bladder cancer stem cells | NA | Gu et al. (2018) |