Table 1.
Minimum inhibitory concentration of the Brazilian Red Propolis crude hydroalcoholic extract, and fractions against periodontopathogenic bacteria.
| Minimum Inhibitory Concentration (µg/mL) | |||||
|---|---|---|---|---|---|
| Crude extract | Fractions | ||||
| Bacteria | Dichloromethane | Ethyl acetate | Hexane | n-Butanol | |
| Porphyromonas gingivalis (ATCC 49417) | 3.12 | 1.56 | 12.5 | 3.12 | 100 |
| Porphyromonas gingivalis (clinical isolate) | 12.5 | 25 | 400 | 100 | – |
| Fusobacterium nucleatum (ATCC 10953) | 100 | 200 | 400 | – | – |
| Fusobacterium nucleatum (clinical isolate) | 12.5 | 12.5 | – | 400 | – |
| Prevotella intermedia (ATCC 15033) | 6.25 | 6.25 | 200 | 200 | 200 |
| Prevotella intermedia (clinical isolate) | 50 | 100 | – | 400 | – |
| Actinomyces naeslundii (ATCC 19039) | 25 | 25 | – | 400 | – |
| Actinomyces naeslundii (clinical isolate) | 100 | 100 | 400 | 400 | 400 |
aTechnique control strains: Bacteroides fragilis (ATCC 25285) and Bacterioides thetaiotaomicron (ATCC 29741)—Metronidazole: 1.47 and 2.95 µg/mL, respectively.—> 400 µg/mL was considered inactive.