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. 2022 Dec 7;13(12):1028. doi: 10.1038/s41419-022-05472-7

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A A sketch illustrating the experimental design. M0 macrophages treated with LV-ETS1 Exos and LV-GFP Exos for 48 h. The effect of the conditioned medium from macrophages treated with exosomes on the proliferation, migration, and invasion of ovarian cancer cells were analyzed by CCK-8 assay, colony-formation assay, Transwell assay and wound-healing assay. B The effect of conditioned medium of macrophages treated with LV-ETS1 Exos and LV-GFP Exos on HO-8910 and A2780 cell proliferation was measured by CCK-8 assay. C The effect of conditioned medium of macrophages treated with LV-ETS1 Exos and LV-GFP Exos on HO-8910 and A2780 cells proliferation was measured by colony-formation assay. D The effect of conditioned medium of macrophages treated with LV-ETS1 Exos and LV-GFP Exos on HO-8910 and A2780 cell migration and invasion were analyzed by Transwell assay. E Wound-healing assay showing the horizontal migration ability of ovarian cancer cells co-cultured with conditioned medium of macrophages treated with LV-ETS1 Exos and LV-GFP Exos. Data are shown as mean ± SD. *P < 0.05, **P < 0.01.