Table 5.
Characteristics Associated with Membership in the Other Two Anxiety and Sleep Disturbance Latent Classes Compared to the No Anxiety and Low Sleep Disturbance Class
| Characteristic | Moderate Anxiety + High Sleep Disturbance |
High Anxiety + Very High Sleep Disturbance |
|---|---|---|
| Demographic Characteristics | ||
| More likely to be younger | ■ | ■ |
| More likely to be female | ■ | |
| Less likely to be married or partnered | ■ | ■ |
| More likely to live alone | ■ | |
| Less likely to be employed | ■ | |
| More likely to have a lower annual household income | ■ | ■ |
| Less likely to exercise on a regular basis | ■ | |
| More likely to self-report as Hispanic, Mixed, or Other | ■ | ■ |
| More likely to have childcare responsibilities | ■ | ■ |
| More likely to have elder care responsibilities | ■ | |
| Clinical Characteristics | ||
| Lower functional status (KPS score) | ■ | ■ |
| Higher chemotherapy toxicity (MAX2 score) | ■ | |
| Higher number of comorbidities | ■ | ■ |
| Higher comorbidity burden (SCQ score) | ■ | ■ |
| More likely to self-report anemia or blood disease | ■ | |
| More likely to self-report depression | ■ | ■ |
| More likely to self-report back pain | ■ | ■ |
| More likely to self-report ulcer or stomach disease | ■ | |
| More likely to self-report kidney disease | ■ | |
| More likely to receive an NK-1 receptor antagonist and two other antiemetics | ■ | ■ |
| Sleep Disturbance Characteristics | ||
| Lower quality of sleep | ■ | ■ |
| Lower quantity of sleep | ■ | ■ |
| Worse sleep onset latency | ■ | ■ |
| Higher level of mid-sleep awakenings | ■ | ■ |
| Higher level of early awakenings | ■ | ■ |
| Higher use of medications for sleep | ■ | ■ |
| Higher level of excessive daytime sleepiness | ■ | ■ |
| Higher level of overall sleep disturbance | ■ | ■ |
| Symptom Characteristics | ||
| Higher depressive symptoms | ■ | ■ |
| Higher trait anxiety | ■ | ■ |
| Higher state anxiety | ■ | ■ |
| Higher morning fatigue | ■ | ■ |
| Higher evening fatigue | ■ | ■ |
| Lower morning energy | ■ | ■ |
| Lower evening energy | ■ | ■ |
| Lower cognitive function | ■ | ■ |
| More likely to report both cancer and non-cancer pain | ■ | ■ |
| Higher worst pain intensity | ■ | ■ |
| Higher pain interference | ■ | ■ |
| Quality of Life Outcomes | ||
| Medical Outcomes Study – Short Form 12 | ||
| Lower physical functioning | ■ | ■ |
| Lower role physical | ■ | ■ |
| Lower bodily pain | ■ | ■ |
| Lower general health | ■ | ■ |
| Lower vitality | ■ | ■ |
| Lower social functioning | ■ | ■ |
| Lower role emotional | ■ | ■ |
| Lower mental health | ■ | ■ |
| Lower physical component summary score | ■ | ■ |
| Lower mental component summary score | ■ | ■ |
| Multidimensional Quality of Life Scale Cancer – Patient Version | ||
| Lower physical well-being | ■ | ■ |
| Lower psychological well-being | ■ | ■ |
| Lower social well-being | ■ | ■ |
| Lower spiritual well-being | ■ | ■ |
| Lower total quality of life score | ■ | ■ |
Abbreviations: KPS, Karnofsky Performance Status; NK-1, neurokinin 1; SCQ, Self-administered Comorbidity Questionnaire.