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. 2022 Aug 6;16(4):1146–1156. doi: 10.1007/s12105-022-01476-z

Fig. 2.

Fig. 2

Base of tongue ACTB::GLI1 fusion-related soft tissue tumor (Case 2). A cellular proliferation of epithelioid cells arranged in nests and anastomosing trabecula (AC) is seen beneath an ulcerated mucosal surface (A). Hyalinized stroma is variably present (B, C) along with occasional intratumoral lymphocytes (C). There is strong nuclear and cytoplasmic, block-like p16 immunoexpression in > 70% of tumor cells (D)