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. 2022 Aug 6;16(4):1146–1156. doi: 10.1007/s12105-022-01476-z

Table 2.

Literature review of GLI1-altered soft tissue tumors primary to the oropharynx

Study Age/Sex Site GLI1 alteration Outcome
Current study 35/M Right palatine tonsil Amplified Recent case
Current study 84/M Base of tongue/vallecula ACTB::GLI1 Recent case
Current study 53/M Oropharynx, not otherwise specified ACTB::GLI1 Recent case
Liu et al. [2] 27/M Tongue base ACTB::GLI1 NED (16 months)
Zhong et al. [4] 56/M Right base of tongue extending to the right oral tongue and lateral pharyngeal wall GLI1 rearrangement

- Local metastasis to right level II neck and distant metastasis to left sacrum 27 months after primary tumor resection

- NED 36 months after neck dissection, resection of sacral mass, and chemotherapy

Klubíčková, et al. [3] 34/F Soft palate and lateral nasopharyngeal wall PTCH1::GLI1 NED (4 months)

NED no evidence of disease