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. 2022 Dec 8;131:106316. doi: 10.1016/j.bioorg.2022.106316

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Fig. 7 — (A) With addition of BA-4 (20 uM), Co-IP assays showed no affection of the binding of SARS-CoV-2 S protein and ACE2 (anti-Flag). (B) BA-4 inhibited SARS-CoV-2 Omicron mutant infection via blocking Omicron protein-mediated membrane fusion. (C) SPR analysis of the interaction between BA-4 with Omicron S2. (D) SPR analysis of the interaction between BA-4 with Omicron S1.