Table 4.
Inhibitory activities of BA-1 and BA-4 against Omicron pseudovirus and other variants.
| varians compds |
EC50a(μM) |
|||||
|---|---|---|---|---|---|---|
| Omicron | Delta | N501Y | D614G | E484K | P681H | |
| BA-1 | 7.04 ± 0.35 | 8.79 ± 0.22 | 5.84 ± 0.60 | 7.70 ± 0.41 | 8.41 ± 0.63 | 9.62 ± 0.50 |
| BA-4 | 4.66 ± 0.52 | 4.25 ± 0.37 | 2.73 ± 0.31 | 3.01 ± 0.25 | 4.75 ± 0.58 | 5.19 ± 0.86 |
a
The samples were examined in 293 T-ACE2 cells in triplicate. 293 T-ACE2 cells were incubated with test compounds and pSARS-CoV-2, and the concentration of test compound resulting in 50 % cell protection was reported as the EC50.