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Pharmacokinetic Parameters After Application of the BH Aqueous Solution and MMt-BH-HA/CS-ED NPs
| Preparations | AUC0-t (mg·min−1·L−1) | MRT0-t (min) |
|---|---|---|
| BH solution | 2011.28±21.59 | 27.18±5.44 |
| MMt-HA/CS-ED NPs | 12811.97±941.50*** | 66.56±1.47** |
Notes: mean ± SD, n = 3, **p < 0.01, ***p < 0.001.
Abbreviations: AUC, area under the curve; MRT, mean residence time.
