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. 2022 Nov 24;9:1023438. doi: 10.3389/fcvm.2022.1023438

Figure 5.

Figure 5

EEEG reduces atherosclerotic plaque areas in HFD-fed ApoE−/− mice. (A) Representative images of Oil-Red-O staining of entire aortas including the aortic arch, thoracic, and abdominal regions. (B–E) Quantitative analysis of aorta lesion areas stained with Oil-Red-O. (F) Representative images of H&E, Oil-Red-O, and Masson staining of aortic root. (G–I) Quantitative analysis of aortic root section lesion areas stained with H&E, Oil-Red-O, and Masson. HFD (n = 12), HFD+1 g/kg EEEG (n = 11), HFD+2 g/kg EEEG (n = 11), HFD+4 g/kg EEEG (n = 12), Data are expressed as mean ± s.e.m., Statistical analysis was based on Graphpad Prism 9.0.2 software and a value of P < 0.05 was considered statistically significant. One-way ANOVA with Student Neuman-Keuls post-hoc test was performed to compare the data between multiple groups, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. HFD.