Table 2.

Populations considered to be “high-risk” for primary aldosteronism: high-risk populations are those in whom it has been demonstrated that the prevalence of primary aldosteronism is very high and mostly unrecognized

High-risk populations
Severe or resistant hypertension
Unexplained or diuretic-induced hypokalemia
Hypertension with adrenal mass
Hypertension with sleep apnea
Hypertension with atrial fibrillation
Strong personal or family history

Debated expansion of eligible populations
New-onset hypertension
Stage 2 hypertension
All hypertension

We suggest that all of these individuals be screened for primary aldosteronism. Beyond these high-risk individuals, there is growing consensus that screening for primary aldosteronism should be expanded to include more populations.