Table 4.
Risk factors associated with early recurrence
| Variable | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Odds ratio | 95% CI | P value | Odds ratio | 95% CI | P value | |
| Age | ||||||
| < 65 | Ref | |||||
| ≥ 65 | 1.56 | 0.53-4.61 | 0.42 | |||
| Gender | ||||||
| Female | Ref | |||||
| Male | 1.31 | 0.55-3.12 | 0.55 | |||
| Differentiation | ||||||
| Well-moderate | Ref | Ref | ||||
| Poor | 1.34 | 0.03-1.50 | 0.01 | 1.06 | 0.01-1.19 | 0.07 |
| pT stage | ||||||
| T1 | Ref | |||||
| T2 | 1.15 | 0.20-6.70 | 0.54 | |||
| T3 | 1.23 | 0.13-2.26 | 0.88 | |||
| T4 | 1.48 | 0.32-6.90 | 0.62 | |||
| Lymph nodes | ||||||
| Negative | Ref | Ref | ||||
| Positive | 3.62 | 1.41-9.29 | 0.007 | 1.38 | 0.11-17.21 | 0.80 |
| Stage | ||||||
| I | Ref | |||||
| II | 0.79 | 0.15-4.03 | 0.77 | |||
| III | 1.36 | 0.61-9.15 | 0.22 | |||
| Lymphovascular invasion | ||||||
| Negative | Ref | Ref | ||||
| Positive | 3.74 | 1.10-12.63 | 0.03 | 2.52 | 0.85-19.63 | 0.06 |
| Adjuvant chemotherapy | ||||||
| Yes | Ref | |||||
| No | 1.23 | 0.39-3.87 | 0.72 | |||
| Adjuvant radiotherapy | ||||||
| No | Ref | Ref | ||||
| Yes | 0.10 | 0.03-0.28 | < 0.001 | 0.17 | 0.01-0.58 | 0.014 |
| Recurrence pattern | ||||||
| Central | 0.38 | 0.02-6.28 | 0.50 | |||
| Sacral | 0.25 | 0.01-8.56 | 0.44 | |||
| Sidewall | 0.176 | 0.01-3.65 | 0.27 | |||
| Composite | Ref | |||||