Table 6.
The significantly differential percentage of promoter methylation in tumor suppressor genes between serous type ovarian cancer tissues and non-serous type ovarian cancer tissues
| Gene name | Number of methylation/all (%) | p-value | |
|---|---|---|---|
|
| |||
| Group 1 | Group 2 | ||
| RASSF1A* | 10/39 (26%) | 34/71 (48%) | 0.023 |
| RASSF1A** | 11/39 (28%) | 36/71 (51%) | 0.022 |
| CDKN2A | 4/39 (10%) | 1/71 (1%) | 0.033 |
| BRCA1 | 11/39 (28%) | 0/71 (0%) | <0.001 |
| SCGB3A1 | 3/39 (8%) | 21/71 (30%) | 0.008 |
| ID4 | 1/39 (3%) | 11/71 (15%) | 0.038 |
| CACNA1A | 3/39 (8%) | 24/71 (34%) | 0.002 |
Note: *group 1: serous type epithelial ovarian cancer tissues; group 2: non-serous type epithelial ovarian cancer tissues;
probe 1: RASSF1A(328);
probe 2: RASSF1A: RASSF1A(382).