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. 2022 Nov 24;10:1024535. doi: 10.3389/fpubh.2022.1024535

Table 3.

Complications, treatment, and outcomes of infected patients during hospitalization.

Patients No. (%)
Cardiac injury
All
n (%)
With
n (%)
Without
n (%)
P value
Complications
Sepsis 1,271 (62%) 411 (66%) 860 (60%) <0.0001
ARDS 677 (33%) 380 (61%) 297 (21%) <0.0001
Respiratory failure 642 (31%) 388 (62%) 254 (18%) 0.001
Septic shock 594 (29%) 295 (47%) 299 (21%) 0.05
Bacteremia 349 (17%) 225 (36%) 124 (9%) 0.48
Hyperglycemia 329 (16%) 131 (21%) 198 (14%) 0.002
Electrolyte disturbance 226 (11%) 126 (20%) 100 (7%) 0.054
Anemia 144 (7%) 81 (13%) 63 (4%) 0.24
Hypoproteinemia 103 (5%) 51 (8%) 52 (4%) 0.63
Coagulopathy 83 (4%) 54 (9%) 29 (2%) 0.05
Acidosis 82 (4%) 27 (4%) 55 (4%) 0.17
Acute kidney injury 41 (2%) 19 (3%) 22 (1%) 0.09
In-hospital treatment
Antibiotic therapy 1,337 (65%) 549 (88%) 788 (55%) 0.001
Antiviral therapy 1,932 (94%) 617 (99%) 1,315 (92%) 0.06
Intravenous corticosteroids 1,601 (78%) 561 (90%) 1,040 (73%) 0.001
High-flow nasal cannula oxygen therapy 1,436 (70%) 139 (22%) 1,297 (91%) <0.0001
Non-invasive mechanical ventilation 266 (13%) 237 (38%) 29 (2%) 0.001
Invasive mechanical ventilation 169 (8%) 126 (20%) 43 (3%) 0.001
ECMO 21 (1%) 21 (3%) 0 0.91
CRRT 41 (2%) 39 (6%) 2 (0.14%) 0.39
Intravenous immunoglobin 1,338 (65%) 534 (86%) 804 (56%) 0.09
Clinical outcomes
Recovered and discharged 1,717 (84%) 326 (52%) 1,391 (97%) 0.001
In-hospital death 334 (16%) 297 (48%) 37 (2%) 0.001

ARDS, Acute respiratory syndrome; ECMO, Extracorporeal membrane oxygenation; CRRT, Continuous renal replacement therapy. The significance threshold is at <0.05 and <0.01.