TABLE 3.
3D structural deviation of mutated A1AT protein structures versus wildtype represented in the form of RMSD values.
| # | dbSNP ID | Amino acid variant | RMSD values (Å) | |
|---|---|---|---|---|
| Whole structure | Amino acid | |||
| 1 | rs1555369172 | F76S | 0.038 | 2.4 |
| 2 | rs55819880 | S77F | 0.028 | 2.9 |
| 3 | rs756773408 | G216C | 0.029 | 3.1 |
| 4 | rs1566753480 | L278P | 0.039 | 2.5 |
| 5 | rs17580 | E288V | 0.049 | 2.8 |
| 6 | rs1555367891 | H358R | 0.069 | 2.9 |