Table 2.

Incidence of adverse reactions

Study	Adverse reaction
	E	C
Zhu W 2020 [11]	Vaginal pain 1 case	Vaginal pain 1 case, pruritus 1 case, fever 1 case
Shun X 2022 [15]	Abdominal distension 3 cases, pruritus 2 cases, vaginal pain 2 cases	Abdominal distension 3 cases, pruritus 3 cases, vaginal pain 2 cases
Li C 2018 [16]	Vaginal uncomfortable 4 cases, fever 3 cases, urine frequency 2 cases	Vaginal uncomfortable 5 cases, fever 3 cases, urine frequency 3 cases
Liu H 2016 [17]	Irritability 1 case	Irritability 1 case, gastrointestinal reaction 1 case
Lai Z 2021 [18]	Vaginal pain 3 cases, vaginal dryness 2 cases	Vaginal pain 1 case, vaginal dryness 3 cases
Li X 2020 [19]	leucorrhea increasing 1 case, rash 1 case	leucorrhea increasing 2 cases, rash 1 case
Wang L 2021 [20]	Vaginal secretion increase 1 case, abnormal leukorrhea 2 cases, vaginal uncomfortable 2 cases	Vaginal secretion increase 3 cases, abnormal leukorrhea 4 cases, vaginal uncomfortable 6 cases
Lai X 2022 [21]	Vaginal uncomfortable 1 case, fever 1 case	Vaginal uncomfortable 3 cases, fever 2 cases, urine frequency 1 case
Yi B 2021 [22]	Vaginal pain 5 cases, abdominal distension 2 cases, vaginal secretion increase 1 case	Vaginal pain 3cases, abdominal distension 2 cases, vaginal uncomfortable 1 case, vaginal secretion increase 1 case
Zhou J 2020 [23]	Pruritus 1 case	Vaginal pain 2 cases, pruritus 3 cases, urine frequency 3 cases

E: experimental group; C: control group.