Table 2.

Within-group analysis of all stress measures comparing positive affect at baseline (t_–1) with time points t₀ (stress reactivity), t₁, and t₂ (all groups recovered) adjusted for age and gender^a.

Stress type			Patients					At-risk					Controls
			b (CI)		P value		b (CI)			P value		b (CI)			P value
Event-related stressb
	t0	–0.35 (–0.43 to –0.28)		<.001c		–0.34 (–0.43 to –0.26)			<.001c		–0.27 (–0.35 to –0.19)			<.001c
	t1	–0.06 (–0.13 to 0.02)		.16		–0.08 (–0.16 to 0.02)			.10		–0.04 (–0.13 to 0.04)			.32
	Age	–0.002 (–0.01 to 0.01)		.52		0.01 (0.002 to 0.02)			.01c		0.01 (0.004 to 0.02)			.001c
	Gender	–0.13 (–0.28 to 0.03)		.11		0.06 (–0.14 to 0.27)			.56		0.001 (–0.16 to 0.16)			.99
Activity-related stressd
	t0	–0.49 (–0.60 to –0.38)		<.001c		–0.54 (–0.68 to –0.40)			<.001c		–0.60 (–0.74 to –0.46)			<.001c
	t1	–0.14 (–0.26 to –0.02)		.02c		–0.17 (–0.33 to –0.02)			.03		–0.15 (–0.30 to 0.001)			.05
	t2	0.008 (–0.12 to 0.13)		.90		–0.09 (–0.25 to 0.07)			.27		–0.09 (–0.24 to 0.06)			.25
	Age	–0.0004 (–0.01 to 0.01)		.92		0.01 (0.004 to 0.02)			.005c		0.009 (0.001 to 0.02)			.03
	Gender	–0.22 (–0.42 to –0.02)		.03		0.05 (–0.21 to 0.30)			.72		0.07 (–0.16 to 0.29)			.55
Composite stress measure
	t0	–0.38 (–0.45 to –0.31)		<.001c		–0.38 (–0.46 to –0.30)			<.001c		–0.32 (–0.40 to –0.25)			<.001c
	t1	–0.11 (–0.19 to –0.04)		.004c		–0.11 (–0.20 to –0.03)			.01		–0.07 (–0.15 to 0.01)			.10
	t2	–0.02 (–0.09 to 0.06)		.66		–0.05 (–0.14 to 0.03)			.23		–0.09 (–0.18 to –0.01)			.03
	Age	–0.001 (–0.01 to 0.01)		.71		0.01 (0.004 to 0.02)			.003c		0.01 (0.003 to 0.02)			.002c
	Gender	–0.12 (–0.27 to 0.03)		.12		0.07 (–0.12 to 0.27)			.47		–0.01 (–0.17 to 0.14)			.88

^aTime point t_–1 (ie, baseline) serves as reference category; effect of female gender is depicted.

^bMissing cases: n_individuals=30; n_prompts=1182.

^cSignificant after Simes correction.

^dMissing cases: n_individuals=348; n_prompts=7680.