Figure 5.

8A ameliorated LPS-induced endotoxemia in mice.A, mice were treated with the indicated doses of 8A (i.g.) once after the LPS challenge (10 mg/kg, i.p.). B, survival rates and body temperature were recorded. C, after LPS challenge with or without 8A treatment for 24 h, mice were sacrificed. Levels of cytokines in serum were measured. There were 10 mice in A and B. Data in C were presented as the mean ± SD of 6 mice. ∗p < 0.05, ∗∗p < 0.01 versus LPS alone treated group. LPS, lipopolysaccharide.