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. 2022 Nov 12;298(12):102696. doi: 10.1016/j.jbc.2022.102696

Figure 6.

Figure 6

8A decreased lung and liver damage in mice with LPS-induced endotoxemia. After the LPS challenge for 24 h, mice were sacrificed. A, representative mouse lung tissue sections were stained with H&E; B, mouse liver tissue sections were stained with H&E. C, levels of pro-inflammatory cytokines in the lung tissue were determined by RT-PCR. D, ALT and AST levels. E, Representative mouse lung tissue sections were subjected to IHC staining for CASP p20. Scale bar 50 μm in A, B and E. Data in C and D were presented as the mean ± SD of six mice. Data in A, B and E were expressed as the mean ± SD of five fields per mouse in each group. ∗p < 0.05, ∗∗p < 0.01 versus LPS alone treated group. ALT, alanine transaminase; AST, aspartate aminotransferase; IHC, immunohistochemistry; LPS, lipopolysaccharide.