Figure 7.

8A decreased colon damage in mice with LPS-induced endotoxemia. After the LPS challenge for 24 h, mice were sacrificed, following which colon damage was evaluated. A and B, by colon length; C, by H&E staining (C). D, levels of pro-inflammatory cytokines in colon tissue were determined using RT-PCR. E, paraffin-embedded colon tissue sections from each group were stained for E-cadherin. F, paraffin-embedded colon tissue sections from each group were stained for CASP1 p20. Data in B and E were presented as the mean ± SD of six mice. Data in D–F were expressed of mean ± SD of five fields per mouse in each group. ∗p < 0.05, ∗∗p< 0.01 versus LPS alone treated group. Scale bar 50 μm in C, E and F. LPS, lipopolysaccharide.