Figure 1.

One-year unisexual infection with male or female schistosomes leads to persistent organ alterations and hepatic inflammation. (A) Representative images of livers and spleens and of liver sections stained with Sirius red (SR) and hematoxylin/eosin (H&E) (magnification 200-fold). (B) Relative organ size of livers and spleens expressed as a ratio to body weight. (C) Serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (AP) in male-infected, female-infected and uninfected (naive) control group mice (52 weeks post-infection, n=4-6). Data are presented as mean ± SEM. P values < 0.05 were considered statistically significant. *p < 0.05, **p < 0.01.