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. 2022 Nov 24;13:1052917. doi: 10.3389/fmicb.2022.1052917

Table 2.

Comparison of differences between the Healthy group, the HBV-free group and the CHB group.

Indexes Healthy group(n = 28) HBV-free group(n = 20) CHB group(n = 45) Healthy vs. CHBt value Healthy vs. CHBp value HBV-free vs. CHBt value HBV-free vs. CHBp value
Age 39.36 ± 1.4500 43.25 ± 2.8040 35.73 ± 1.4930 1.638 0.1059 2.581 0.0122
TBIL 13.23 ± 0.6905 11.32 ± 0.9489 15.78 ± 1.1730 1.612 0.1113 2.381 0.0203
DBIL 2.38 ± 0.1391 2.31 ± 0.2913 2.73 ± 0.1860 1.349 0.1815 1.245 0.2179
IBIL 10.85 ± 0.5816 8.80 ± 0.7396 13.05 ± 1.0030 1.629 0.1077 2.676 0.0095
TP 71.40 ± 0.7522 69.99 ± 1.7410 71.31 ± 0.6065 0.0951 0.9245 0.8957 0.3738
ALB 42.31 ± 0.3893 42.12 ± 0.9505 42.52 ± 0.3661 0.3694 0.7129 0.4829 0.6308
γ-GT 37.07 ± 6.5700 32.28 ± 3.7140 29.70 ± 3.4390 1.089 0.2799 0.4497 0.6545
ALT 20.01 ± 2.3380 31.51 ± 2.6540 33.57 ± 4.7790 2.137 0.036 0.2779 0.782
AST 20.36 ± 1.1490 25.08 ± 1.0280 26.33 ± 1.6710 2.585 0.0118 0.4801 0.6328
AST/ALT 1.21 ± 0.0766 0.85 ± 0.0459 1.05 ± 0.0762 1.421 0.1598 1.656 0.1027
GLB 29.09 ± 0.6338 27.80 ± 0.9000 28.79 ± 0.4340 0.4011 0.6896 1.119 0.2673
A/G 1.48 ± 0.0355 1.53 ± 0.0491 1.49 ± 0.0247 0.384 0.7021 0.8495 0.3988
HBeAg 0.12 ± 0.0017 0.10 ± 0.0021 179.90 ± 63.8200 2.216 0.0299 1.87 0.0661
HBeAb 1.21 ± 0.0966 1.25 ± 0.1408 0.89 ± 0.2505 0.9641 0.3383 0.9153 0.3635
HBcAb 1.51 ± 0.2016 1.29 ± 0.2546 0.05 ± 0.0364 8.849 <0.0001 7.042 <0.0001
CXCL8 112.80 ± 9.5560 227.8 ± 13.7800 2,842 ± 82.5600 25.94 <0.0001 20.96 <0.0001
CXCL9 140.40 ± 10.6700 2096 ± 117.7000 3,609 ± 128.6000 21.2 <0.0001 7.252 <0.0001
CXCL10 118.70 ± 10.1700 317.9 ± 21.4100 2,234 ± 35.2300 46.5 <0.0001 34.88 <0.0001
CXCL11 153.10 ± 11.5500 2,774 ± 157.8000 4,735 ± 181.4000 19.86 <0.0001 6.709 <0.0001

Comparisons were made using t-test analysis.

TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; TP, total protein; ALB, albumin, γ-GT γ-glutamyl transpeptidase; ALT, alanine aminotransferase; AST, aspartate transaminase; AST/ALT, ratio of aspartate aminotransferase to alanine aminotransferase; GLB, globulin, A/G ratio of albumin to globulin; HBeAg, hepatitis B e antigen; HBeAb, hepatitis B e antibody; HBcAb, hepatitis B core antibody.