TABLE 2.

The most recent recombinant protein expression systems in Pichia pastoris.

Vector name	Used strain	Promoter	Recombinant protein	Yield	References
pPICαA-rlys	X-33	AOX1	Lysostaphin	1,141 mg/L	Shen et al., 2021
pPIC9k	GS115	AOX1	Human epidermal growth factor (hEGF)	2.27 mg/L	Eissazadeh et al., 2017
pPICZαA	GS115	AOX1	Antimicrobial peptide (Hispidalin)	98.6 mg/L	Meng et al., 2019
pPICZαA	GS115	AOX1	Antimicrobial peptide (PaDef)	unknown	De-Mei et al., 2017
pPIC9K	GS115	AOX1	Aspartic proteases	4.5 g/L	Qian et al., 2018
pAO815	SMD116	AOX	Manganese peroxidase (MnP)	126 mg/L	Xu et al., 2017
pPICZ	KM71H	AOX1	Human ATP-binding cassette	0.5 mg/L	Lee et al., 2017
pGAPZ	GS115	GAP	Tachyplesin 1 (TP1)	27.24–29.53 mg/L	Lia et al., 2019
pPICZαA	X-33	AOX	Human telomerase inhibitor 1 (hPinX1)	unknown	Unver et al., 2018
pD902	BG10	AOX1	Human papillomavirus type 52	128.015 mg/L	Dewi et al., 2022
pPICZαB	GS115	AOX1	Dengue virus NS1 protein	2.18 mg/L	Allonso et al., 2019
pPICZαA	GS115	AOX1	Recombinant α-carbonic anhydrase	47.5 mg/L	Faridi and Satyanarayana, 2018