Table 2.
Indications and outcomes of liver transplantation and alternative treatments for children affected by benign vascular tumours of the liver reported in literature.
| patients (N) | LT (N) | Indication for LT | Treatments other than LT | alive total n /LT | follow-up | |
|---|---|---|---|---|---|---|
| Kuroda (2014) | 19 | 1 | liver failure | prednisolone(n=13), radiation therapy (n=2), embolization (n=1), liver resection (n=3) | 1 | not reported |
| Markiewicz (2009) | 4 | 4 | heart failure non responsive to embolization | steroids+vincristine (n=1), embolization(n=1), hepatic artery ligation (n=2) | 4 | 6-36 months |
| Zenzen (2009) | 1 | 1 | hemodinamic and hepatic impairment | steroids+embolization | 1 | not reported |
| Samuk (2015) | 3 | 3 | cardiovascular impairment, life-threatening complications | not reported | 3 | 74-168months |
| Balazs (2007) | 1 | 1 | hypothyroidism, respiratory distress, abdominal distention | steroids | 1 | 6 months |
| Lee (2006) | 1 | 1 | hypothyroidism, respiratory failure | steroids+vincristine | 1 | 7 months |
| Lopez-Gutierrez (2019) | 31 | 3 | not reported | propranololo (n=11) | 27 (LT=3) [4 deathts while on LT waiting list] | not reported |
| Kulungowski (2012) | 121 | 2 | heart failure resistent to medical treatment | no treatment (n=51); steroids (n=15); steroids+vincristine/propanolol/IFN (n=17); IFN(n=2); propranololo (n=1); liver resection (n=2); unkonown (n=31) | 114 [LT not reported] | not reported |
| Dickie (2009) | 26 | 1 | progressive caridac failure not responsive to medical therapy | no treatment (n=13); intralesion glucocorticoids injection (n=1); systemicglucocorticoids (n=7); systemic glucorticoids+vincristine (n=2); liver resection (n=1);levothyroxine (n=1);systemic glucorticoids+IFN+LT (n=1 | 26 [LT=1] | 3-8 months |
LT, liver transplantation; IFN, interferon.