Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 7;22:385. doi: 10.1186/s12935-022-02809-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 6 — AKR1B10 is highly expressed in CCA tissues. A AKR1B10 expression in the GEPIA2 dataset. The red box indicates tumor tissue, and the gray box indicates normal tissue. B Representative image of AKR1B10 expression in tumor and peritumoral tissue in the CCA tissue microarray. Compared with that in peritumoral tissues, AKR1B10 was overexpressed in CCA tissues, as revealed by IHC staining for AKR1B10 in a CCA tissue microarray (n = 60). Scale bar: 500 μm. C The AKR1B10 score in CCA tissues was significantly higher than that in peritumoral tissues. The sample sizes were 60 in CCA tumor and peritumoral tissues. D Representative image of AKR1B10 expression at four levels in the CCA tissue microarray. AKR1B10 expression was scored at four levels (no staining, weak, moderate, strong) on the basis of IHC staining intensity. Scale bar: 500 μm. E Pearson correlation analysis of the IHC scores between METTL3 and AKR1B10. *Means P < 0.05, **means P < 0.01