Table 2.

Prolongation of Autofluorescence Lifetime in Ectopic RPE

		τm SSC [ps]				τm LSC [ps]
	n	Median	IQR	P vs. Normal Ageing	Effect Size r	Median	IQR	P vs. Normal Ageing	Effect Size r
Normal aging	112	180	44			250	55
Very nonuniform	133	226	51	<0.001	0.47	317	43	<0.001	0.51
Sloughed	21	243	89	<0.001	0.44	362	104	<0.001	0.49
IntraPS	63	302	73	<0.001	0.88	395	80	<0.001	0.92
IntraELM	109	320	86	<0.001	1.10	441	76	<0.001	1.19
Bilaminar	24	230	36	0.001	0.35	310	25	0.001	0.35
Dissociated	27	218	42	0.023	0.28	328	37	<0.001	0.43
Subducted	5	376	154	—		480	123	—
Shedding	3	230		—		313		—

Changes in RPE morphology are accompanied by a prolongation of mean autofluorescence lifetime (τ_m) after TPE excitation at 960 nm. n = number of ROIs, results are given as median with interquartile range (IQR). Statistic by Kruskal-Wallis with Dunn-Bonferroni post hoc test. Corrected P values for normal aged RPE are indicated. SSC, short-wavelength spectral channel (500-550 nm); LSC, long-wavelength spectral channel (550-700 nm).