. 2022 Dec;63(12):1809–1814. doi: 10.2967/jnumed.121.263707

TABLE 2.

Template-Based Analysis

¹⁸F-rhPMSA-7.3 PET/CT rating	Histology: lymph node metastasis		Proportions
¹⁸F-rhPMSA-7.3 PET/CT rating	Positive	Negative	Proportions
Combined data for ¹⁸F-rhPSMA-7 and ¹⁸F-rhPSMA-7.3
Positive	61	5	PPV: 92.4% (95% CI, 83.3%–96.8%)
Negative	14	70	NPV: 83.3% (95% CI, 72.2%–90.6%)
Total	75	75	150
	Sensitivity: 81.3% (95% CI, 70.1%–89.0%)	Specificity: 93.3% (95% CI, 85.9%–97.0%)	Accuracy: 87.3% (95% CI, 80.5–92.0)
Morphologic imaging (CT/MRI)
Positive	9	0	PPV: 100% (95% CI, N/A)
Negative	66	75	NPV: 53.2% (95% CI, 44.5%–61.6%)
Total	75	75	150
	Sensitivity: 12.0% (95% CI, 6.3%–21.6%)	Specificity: 100% (95% CI, N/A)	Accuracy: 64.5% (95% CI, 47.2%–64.5%)

Scores ≥ 4 in PET and morphologic imaging rated positive.

NPV = negative predictive value; N/A = not available as cannot be calculated (there exists no CI for point estimator of 1 in a generalized estimating equation).