TABLE 1.
Baseline Characteristics of HEPAR Primary Patients (n = 31)
| Characteristic | Data | % or range |
|---|---|---|
| Sex | ||
| Female | 3 | 10 |
| Male | 28 | 90 |
| Age (y) | 73 | 44–85 |
| Cirrhosis on imaging | 20 | 65 |
| Underlying liver disease* | ||
| Alcohol abuse | 20 | 65 |
| Hepatitis B | 1 | 3 |
| Hepatitis C | 4 | 13 |
| Nonalcoholic fatty liver disease | 3 | 10 |
| Hemochromatosis | 2 | 4 |
| None of above | 6 | 20 |
| BCLC | ||
| B | 22 | 71 |
| C | 9 | 29 |
| Bilirubin (μmol/L) | 12 | 4–29 |
| Albumin (g/L) | 38.5 | 31–41.9 |
| International normalized ratio | 1.22 | 0.94–1.94 |
| Thrombocytes (×109/L) | 132 | 75–464 |
| Child–Pugh score | ||
| A5 | 19 | 61 |
| A6 | 9 | 29 |
| B7 | 3 | 10 |
| Model-for-end-stage-liver-disease score | 9 | 6–16 |
| ECOG performance status | ||
| 0 | 18 | 58 |
| 1 | 13 | 42 |
| Extrahepatic lesions | ||
| None | 27 | 87 |
| Adrenal glands | 4 | 13 |
| Portal hypertension | ||
| Thrombocytes < 150 | 18 | 58 |
| Varices | ||
| Small | 9 | 29 |
| Large | 2 | 6 |
| Imaging | 14 | 45 |
| Portal vein thrombosis | 6 | 19 |
| Tumor thrombus | 4 | 13 |
| Nontumor thrombus | 1 | 3 |
| Mixed type | 1 | 3 |
| Bilobar disease† | 17 | 55 |
| Number of tumors | ||
| 1 | 4 | 13 |
| 2–3 | 4 | 13 |
| >3 | 23 | 74 |
| Tumor burden (%) | 9.3 | 0.5–46.8 |
| Largest tumor diameter (mm) | 56 | 15‡–195 |
| Previous treatment¶ | ||
| None | 26 | 84 |
| Resection | 4 | 13 |
| Ablation | 4 | 13 |
| Transarterial chemoembolization | 1 | 1 |
*
Some patients had more than 1 underlying liver problem.
†
Only Liver Imaging Reporting and Data System 5 (definitely HCC) lesions were considered.
‡
Patient had more than 15 small lesions.
¶
Some patients had more than 1 previous treatment.
Qualitative data are number and percentage; continuous data are median and range.