TABLE 3.
Results of the Univariate Analyses for PFS and OS Using Time-Dependent AUC Analysis and Cox Models (HR)
| 3D 18F-FDG PET/CT estimates | 2D PET MIP estimates | |||||
|---|---|---|---|---|---|---|
| Data | PFS/OS | Metrics | TMTV | Dmax | sTMTV | sDmax |
| REMARC | PFS | AUC | 0.67 (0.60–0.73) | 0.65 (0.58–0.72) | 0.65 (0.58–0.72) | 0.68 (0.62–0.75) |
| HR | 11.24 (2.10–46.20) | 9.0 (2.53–23.63) | 11.81 (3.29–31.77) | 12.49 (3.42–34.50) | ||
| OS | AUC | 0.67 (0.58–0.76) | 0.62 (0.53–0.71) | 0.67 (0.58–0.76) | 0.68 (0.59–0.76) | |
| HR | 16.43 (2.42–77.29) | 8.60 (1.47–28.33) | 22.14 (4.73–69.06) | 22.79 (3.80–79.21) | ||
| LNH073B | PFS | AUC | 0.62 (0.49–0.75) | 0.56 (0.39–0.72) | 0.66 (0.53–0.80) | 0.58 (0.41–0.74) |
| HR | 13.79 (0.45–86.80) | 32.83 (0.4–220.8) | 9.24 (0.95–37.94) | 16.79 (0.69–86.41) | ||
| OS | AUC | 0.65 (0.46–0.82) | 0.51 (0.31–0.72) | 0.64 (0.45–0.82) | 0.50 (0.29–0.72) | |
| HR | 64.30 (0.74–384.80) | 49.21 (0.07–258.3) | 14.17 (0.59–67.02) | 20.39 (0.08–93.66) | ||