TABLE 2.
Appearance of MAdCAM-1- and ICAM-1-expressing venules throughout the course of a genital MoPn infection
| Adhesion molecule and region | Mean no. of venules expressing adhesion molecule/mm2 of tissue (± SEM) on day:
|
||||
|---|---|---|---|---|---|
| 0 | 7 | 14 | 21 | 35 | |
| MAdCAM-1 | |||||
| CV | 0.04 (0.01) | 3.90 (1.88) | 0.50 (0.40) | 1.14 (0.74) | 0.04 (0.00) |
| UH | 0.02 (0.00) | 0.02 (0.00) | 0.43 (0.36) | 1.42 (0.88) | 0.42 (0.39) |
| OD | 0.09 (0.03) | 0.09 (0.04) | 1.07 (0.55) | 0.43 (0.39) | 0.52 (0.47) |
| ICAM-1 | |||||
| CV | 9.92 (1.25) | 10.85 (1.74) | 6.30 (1.12) | 7.0 (2.87) | 3.94 (1.3) |
| UH | 0.02 (0.00) | 4.89 (2.04) | 9.18 (4.94)a | 15.2 (2.73)a | 1.78 (1.58) |
| OD | 0.09 (0.03) | 0.42 (0.29) | 5.22 (3.35) | 9.10 (4.74) | 1.13 (1.09) |
a
There was a significant increase in the number of venules compared to day 0 values; P < 0.05 by ANOVA and Dunn's post-hoc test.