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Age-related IgG levels of LPS antibody in serum before and 180 days after vaccination with SPA-TT conjugates
| Age (yr) | Conjugate | No. of injections | GM LPS antibody titer (EU) on days after vaccination:
|
Fold rise at 180 days | |||
|---|---|---|---|---|---|---|---|
| 0 | 42 | 68 | 180 | ||||
| 18–44 | SPA-TT1 | 1 | 1.26 | 9.82 | NAa | 3.73 | 3.0 |
| SPA-TT2 | 1 | 1.69 | 27.3 | NA | 8.28 | 4.9 | |
| 13–17 | SPA-TT1 | 1 | 1.69 | 12.8 | NA | 6.72 | 4.0 |
| SPA-TT2 | 1 | 1.70 | 17.4 | NA | 7.37 | 4.3 | |
| 2–4 | SPA-TT2 | 1 | 0.91 | 19.3 | 11.7 | 3.47 | 3.8 |
| SPA-TT2 | 2 | 0.77 | 16.7 | 11.9 | 4.08 | 5.3 | |
NA, not applicable.
