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. Author manuscript; available in PMC: 2022 Dec 8.
Published in final edited form as: Optica. 2022 Aug 29;9(9):1009–1021. doi: 10.1364/optica.464700

Fig. 1.

Fig. 1.

Overview of the computational miniature mesoscope (CM2) V2. (a) CM2 V2 hardware platform features miniature LED illuminators for high-efficiency excitation, hybrid filters for spectral leakage rejection, and a BSI CMOS sensor for high-SNR measurement. (b) Photo of the assembled CM2 V2 prototype. (c) Example CM2 measurement from a volume consisting of 10-μm fluorescent beads. (d) CM2Net combines view demixing (demix), view synthesis (synthesis) and light-field refocusing (RF) enhancement (enhance) modules to achieve high-resolution, fast, and artifact-free 3D reconstruction. (e) CM2Net reconstruction from the measurement in (c), spanning a 7 mm FOV and 800-μm depth range.