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Association between cerebrovascular response to exercise (CVR) and amyloid-β (Aβ) deposition in APOE4 carriers (A) and noncarriers (B). Higher CVR was associated with lower levels of Aβ deposition in female APOE4 carriers (r=−.54, p=.048), while showing no relationship in male APOE4 carriers (r=−.17, p=.716) (A). Similarly, CVR and Aβ were negatively associated in male noncarriers (r=−.64, p=.008), and showed a similar pattern in female noncarriers (r=−.29, p=.09) (B).
