. Author manuscript; available in PMC: 2022 Dec 8.

Published in final edited form as: Addict Biol. 2022 Feb 1;27(2):e13143. doi: 10.1111/adb.13143

TABLE 3.

DASS scores for the three groups at screening, on Day 1 before drug administration and 3–4 days after the final drug administration session

	Placebo Mean ± SD	13 μg Mean ± SD	26 μg Mean ± SD
Depression score
Screen	6.2 (5.9)	6.1 (6.7)	7.5 (5.5)
Session 1	3.6 (3.9)	3.7 (3.9)	4.9 (3.9)
Session 5	2.9 (3.0)	2.7 (2.9)	4.5 (3.7)
Anxiety score
Screen	3.1 (3.6)	2.1 (2.2)	2.2 (2.5)
Session 1	1.6 (2.3)	1.7 (2.4)	2.1 (2.3)
Session 5	2.4 (2.9)	0.89 (1.1)	1.4 (1.6)
Stress score
Screen	5.4 (4.3)	4.9 (3.7)	6.3 (4.6)
Session 1	3.8 (2.5)	4.1 (3.5)	6.3 (3.7)
Session 5	3.9 (3.1)	3.6 (3.2)	5.3 (3.4)
DASS total score
Screen	14.8 (12.6)	13.2 (11.4)	15.9 (10.5)
Session 1	9.1 (7.7)	9.5 (8.6)	13.3 (8.6)
Session 5	9.2 (8.3)	7.2 (6.0)	11.2 (8.1)

Notes: Two-way ANOVA for depression score: Drug, ns; Session, F_2,106 = 20.47, p = 0.001; Drug × session, ns. Two-way ANOVA for anxiety score: Drug, ns; Session, F_2,106 = 4.42, p = 0.014; Drug × session, ns. Two-way ANOVA for stress score: Drug, ns; Session, F_2,106 = 4.82, p = 0.010; Drug × session, ns. Two-way ANOVA for total DASS score: Drug, ns; Session, F_2,106 = 15.1, p = 0.001; Drug × session, ns.