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. 2022 Nov 24;9:1058431. doi: 10.3389/fmed.2022.1058431

TABLE 4.

Platelet-rich plasma preparation protocols of included primary cicatricial alopecia studies.

References No. of session Interval Max F/U Route of application Protocol/rpm or G Activator Blood volume/PRP volume
Case series/case reports
Bolanča et al. (56) 3 4 weeks 12 weeks Intralesional injection Double spin method
● 500 G–10 min
● 1520 G–10 min
NR 15/3 ml
Jha (57) 4 3 weeks 12 weeks Intralesional injection NR NR NR/NR
Özcan et al. (58) 5 4 weeks 20 weeks Intralesional injection (0.1 ml/cm2) Single spin method
● 4000 rpm–10 min
NR 14 ml/NR
Jha (59) 4 3 weeks 12 weeks Intralesional injection NR NR NR/NR
Dina and Aguh (60) 3 4 weeks 12 weeks NR Single spin method
● 1100 G–6 min
0.5-M CaCl2 9/4–4.2 ml
3 4 weeks 12 weeks NR Single spin method
● 1100 G–6 min
0.5-M CaCl2 9/4–5 ml
Svigos et al. (61) Until disease stable NR NR Intralesional injection NR NR NR/NR
Suh et al. (62) 3 4 weeks 12 weeks NR Single spin method
● 1100 G–6 min
0.5-M CaCl2 9/4–5 ml
3 6–9 weeks 20 weeks NR NR NR NR/NR
Polster et al. (63) 3 12 weeks 36 weeks Intralesional injection Single spin method
● 3500 rpm–10 min
NR 22/7 ml
Klein et al. (64) 3 4 weeks 12 weeks Intralesional injection (0.1 ml/cm2) Single spin method NR NR/5 ml

CaCl2, calcium chloride; FCL, fractional CO2 laser; G, gravitational force; NR, not reported; PRP, platelet rich plasma; rpm, revolutions per minute.