TABLE 4.
Platelet-rich plasma preparation protocols of included primary cicatricial alopecia studies.
| References | No. of session | Interval | Max F/U | Route of application | Protocol/rpm or G | Activator | Blood volume/PRP volume |
| Case series/case reports | |||||||
| Bolanča et al. (56) | 3 | 4 weeks | 12 weeks | Intralesional injection | Double spin method ● 500 G–10 min ● 1520 G–10 min |
NR | 15/3 ml |
| Jha (57) | 4 | 3 weeks | 12 weeks | Intralesional injection | NR | NR | NR/NR |
| Özcan et al. (58) | 5 | 4 weeks | 20 weeks | Intralesional injection (0.1 ml/cm2) | Single spin method ● 4000 rpm–10 min |
NR | 14 ml/NR |
| Jha (59) | 4 | 3 weeks | 12 weeks | Intralesional injection | NR | NR | NR/NR |
| Dina and Aguh (60) | 3 | 4 weeks | 12 weeks | NR | Single spin method ● 1100 G–6 min |
0.5-M CaCl2 | 9/4–4.2 ml |
| 3 | 4 weeks | 12 weeks | NR | Single spin method ● 1100 G–6 min |
0.5-M CaCl2 | 9/4–5 ml | |
| Svigos et al. (61) | Until disease stable | NR | NR | Intralesional injection | NR | NR | NR/NR |
| Suh et al. (62) | 3 | 4 weeks | 12 weeks | NR | Single spin method ● 1100 G–6 min |
0.5-M CaCl2 | 9/4–5 ml |
| 3 | 6–9 weeks | 20 weeks | NR | NR | NR | NR/NR | |
| Polster et al. (63) | 3 | 12 weeks | 36 weeks | Intralesional injection | Single spin method ● 3500 rpm–10 min |
NR | 22/7 ml |
| Klein et al. (64) | 3 | 4 weeks | 12 weeks | Intralesional injection (0.1 ml/cm2) | Single spin method | NR | NR/5 ml |
CaCl2, calcium chloride; FCL, fractional CO2 laser; G, gravitational force; NR, not reported; PRP, platelet rich plasma; rpm, revolutions per minute.