Table 1. Survey domains and measurements obtained in the ALTERNATIVE survey cohort.

Domain	Measurement
Demographics	Race
	Hispanic ethnicity
	Preferred language
	Education level
	Household income
	Marital status
Medical History	Prior VTE (deep vein thrombosis and/or pulmonary embolism)
	Atrial fibrillation
	Heart valve replacement
	Hypercoagulable condition
	Family history of thrombosis
Anticoagulant Treatment History	Prescription for anticoagulants (warfarin, DOACs)
	Therapeutic change of oral anticoagulants and reasons for change
	Bleeding complications from anticoagulants
	Early discontinuation of anticoagulants and reasons why
	Exposure to non-prescription medications that increase bleeding risk (e.g., aspirin, NSAIDS)
Health-related Quality of Life	SF-36 instrument [23]
	• Self-rated health
	• Physical functioning scale
	• Role limitation physical scale
	• Role limitation emotional scale
	• Energy fatigue scale
	• Emotional well-being scale
	• Social functioning scale
	• Pain scale
	• Physical component summary
	• Mental
Anticoagulation Treatment Satisfaction	ACTS instrument [24]
	• Benefit scale
	• Burden scale
Health Proficiency	Health literacy [25, 26]