Table 3. P-values of non-B-DNA summed probabilities or scores, and distances to breakpoints.
Sum of probabilities or relative scores of non-B-DNA structures within +/-200 bp of breakpoint* | ||||||
Non-B-DNA | Mean obs. | Mean random | Diff of means | 95% CI lower | 95% CI upper | P-value |
melt | 0.041 | 0.121 | -0.08 | -0.26 | 0.10 | 0.380 |
Z-DNA | 1.577 | 1.839 | -0.26 | -2.16 | 1.63 | 0.782 |
cruciform | 0.000 | 0.000 | 0.00 | 0.00 | 0.00 | NA |
triplex | 0.933 | 0.300 | 0.63 | -0.82 | 2.08 | 0.385 |
G4 | 16.094 | 2.640 | 13.45 | 4.60 | 22.31 | 0.004 |
Average distance to closest non-B-DNA structure with probability / relative score >0.2 | ||||||
Non-B-DNA | Mean obs. | Mean random | Diff of means | 95% CI lower | 95% CI upper | P-value |
melt | 450.258 | 498.200 | -47.94 | -89.12 | -6.765 | 0.024 |
Z-DNA | 278.516 | 327.560 | -49.04 | -154.86 | 56.769 | 0.357 |
cruciform | >500 | >500 | NA | NA | NA | NA |
triplex | 433.871 | 442.200 | -8.33 | -77.06 | 60.405 | 0.809 |
G4 | 308.645 | 460.480 | -151.83 | -235.30 | -68.371 | 0.0007 |
* Probabilities are shown for melt, Z-DNA and cruciform; relative scores are shown for triplex and G4.