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. 2022 Nov 28;18(11):e1010524. doi: 10.1371/journal.ppat.1010524

Table 3. P-values of non-B-DNA summed probabilities or scores, and distances to breakpoints.

Sum of probabilities or relative scores of non-B-DNA structures within +/-200 bp of breakpoint*
Non-B-DNA Mean obs. Mean random Diff of means 95% CI lower 95% CI upper P-value
melt 0.041 0.121 -0.08 -0.26 0.10 0.380
Z-DNA 1.577 1.839 -0.26 -2.16 1.63 0.782
cruciform 0.000 0.000 0.00 0.00 0.00 NA
triplex 0.933 0.300 0.63 -0.82 2.08 0.385
G4 16.094 2.640 13.45 4.60 22.31 0.004
Average distance to closest non-B-DNA structure with probability / relative score >0.2
Non-B-DNA Mean obs. Mean random Diff of means 95% CI lower 95% CI upper P-value
melt 450.258 498.200 -47.94 -89.12 -6.765 0.024
Z-DNA 278.516 327.560 -49.04 -154.86 56.769 0.357
cruciform >500 >500 NA NA NA NA
triplex 433.871 442.200 -8.33 -77.06 60.405 0.809
G4 308.645 460.480 -151.83 -235.30 -68.371 0.0007

* Probabilities are shown for melt, Z-DNA and cruciform; relative scores are shown for triplex and G4.