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Recoveries of elimusertib from human plasma and respective matrix effects in human plasma extract, with coefficients of variation (CV).
| Concentration (μg/mL) |
Recovery (%) |
CV (%) |
Matrix effect (%) |
CV (%) |
|---|---|---|---|---|
| 40 (QCL) | 106.7 | 4.8 | 3.7 | 4.2 |
| 200 (QCM | 110.0 | 5.7 | 1.6 | 4.9 |
| 4000 (QCH) | 113.1 | 4.5 | −1.5 | 3.4 |
n=4, for each concentration. QCL, QC Low; QCM, QC Mid; QCH, QC High
