TABLE 1.

Effect of monocyte supernatant fluids on IgG2 production^a

Cultured NP lymphocytes	Origin of Mφb fluids	Mean IgG2 concn (ng/ml) ± SE	n	P
PBL	None	136 ± 10	6
T + B	NP Mφ	146 ± 20	6	NSd
T + B	LJP Mφ	422 ± 49c	5	<0.01

^aThe final culture contained 50% fresh medium and 50% supernatant fluid. 

^bMφ, macrophage. 

^cSignificantly different from PBL cultured in the absence of macrophage supernatant fluids. 

^dNS, not significantly different from PBL cultured in the absence of macrophage supernatant fluids.