Table 1.
Clinical characteristics of the patients and features of the lesions.
| Patients | AMC group, N=82 | Thymomas, N=119 | P-value | Low risk thymomas, N=72 | High risk thymomas, N=47 | P-value |
|---|---|---|---|---|---|---|
| Sex, (％) | 0.935 | 0.247 | ||||
| Male | 37 (45.1%) | 54.02 (44.5%) | 29 (40.3%) | 24 (51.1%) | ||
| Female | 45 (54.9%) | 66 (55.5%) | 43 (59.7%) | 23 (48.9%) | ||
| Age, years | 0.831 | 0.839 | ||||
| Mean ± SD | 53.66 ± 10.57 | 54.02 ± 12.43 | 55.14 ± 12.38 | 52.30 ± 12.43 | ||
| Range | 31-77 | 21-73 | 19-78 | 22-71 | ||
| Symptoms, (％) | 0.001 | 0.398 | ||||
| Myasthenia gravis | 2 (2.4%) | 24 (20.2%) | 13 (18.1%) | 11 (23.4%) | ||
| Chest pain | 4 (4.9%) | 13 (10.9%) | 10 (13.9%) | 3 (6.4%) | ||
| Respiratory symptoms (cough, dyspnea) | 11 (13.4%) | 12 (10.1%) | 9 (12.5%) | 3 (6.4%) | ||
| Other symptom | 9 (11%) | 13 (10.9%) | 6 (8.3%) | 7 (14.9%) | ||
| NO symptom | 56 (68.3%) | 57 (47.9%) | 34 (47.2%) | 23 (48.9%) | ||
| Average CT value, HU, mean ± SD, | 26.83 ± 20.94 | 41.33 ± 11.15 | < 0.001 | 40.38 ± 12.57 | 42.79 ± 8.46 | 0.130 |
| Size, mean ± SD, | ||||||
| maximum diameter on axial image (cm) | 3.44 ± 2.23 | 4.83 ± 2.32 | < 0.001 | 4.99 ± 2.61 | 4.60 ± 1.80 | 0.010 |
| minimum diameter on axial image (cm) | 2.35 ± 1.46 | 3.25 ± 1.54 | < 0.001 | 3.44 ± 1.749 | 2.96 ± 1.09 | < 0.001 |
| Long size on sagittal or coronal image (cm) | 4.62 ± 2.66 | 5.43 ± 2.38 | 0.943 | 5.71 ± 2.57 | 5.00 ± 2.01 | 0.051 |
| Ratio of max to min diameter * |
2.07 ± 0.58 | 1.84 ± 0.61 | 0.007 | 1.82 ± 0.63 | 1.87 ± 0.58 | 0.624 |
| Density uniformity, (％) | < 0.001 | 0.098 | ||||
| yes | 66 (80.5%) | 41 (34.5%) | 29 (40.3%) | 12 (25.5%) | ||
| no | 16 (19.5%) | 78 (65.5%) | 43 (59.7%) | 35 (74.5%) | ||
| Calcification, (％) | 0.023 | 0.174 | ||||
| yes | 10 (12.2%) | 30 (25.2%) | 15 (20.8%) | 15 (31.9%) | ||
| no | 72 (87.8%) | 89 (74.8%) | 57 (79.2%) | 32 (68.1%) | ||
| Shape, (％) | 0.014 | 0.619 | ||||
| round | 13 (15.9%) | 40 (33.6%) | 26 (36.1%) | 14 (29.8%) | ||
| oval | 28 (34.1%) | 37 (31.1%) | 23 (31.9%) | 14 (29.8%) | ||
| irregular | 41 (50%) | 42 (35.3%) | 23 (31.9%) | 19 (40.4%) | ||
| Margin, (％) | < 0.001 | < 0.001 | ||||
| Circumscribed | 43 (52.4%) | 25 (21%) | 22 (30.6%) | 3 (6.4%) | ||
| Lobulated | 28 (34.1%) | 35 (29.4%) | 24 (33.3%) | 11 (23.4%) | ||
| Spiculated | 11 (13.4%) | 59 (49.6%) | 26 (36.1%) | 33 (70.2%) | ||
| Vascular invasion, (％) | 0.238 | 0.078 | ||||
| yes | 0 (0%) | 2 (1.7%) | 0 (0%) | 2 (4.3%) | ||
| no | 82 (100%) | 117 (98.3%) | 72 (100%) | 45 (95.7%) | ||
| Pericardial effusion, (％) | 0.217 | 0.702 | ||||
| yes | 7 (8.5%) | 17 (14.3%) | 11 (15.3%) | 6 (12.8%) | ||
| no | 75 (91.5%) | 102 (85.7%) | 61 (84.7%) | 41 (87.2%) | ||
| Pleural effusion, (％) | 0.017 | 0.905 | ||||
| yes | 0 (0%) | 8 (6.7%) | 5 (6.9%) | 3 (6.4%) | ||
| no | 82 (100%) | 111 (93.3%) | 67 (93.1%) | 44 (93.6%) | ||
| Lymph node, (％) enlargement | 0.039 | 0.024 | ||||
| yes | 0 (0%) | 6 (5%) | 1 (1.4%) | 5 (10.6%) | ||
| no | 82 (100%) | 113 (95%) | 71 (98.6%) | 42 (89.4%) |
SD, standard deviation.