Table 1.
Name | Source | Mechanism of resistance to COL | MIC of COL | BAI Microdilution assay (mg/L) |
Conclusion effect | EDTA Microdilution assay (mg/L) |
Conclusion effect | BAI and EDTA Microdilution assay (mg/L) |
Conclusion effect | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MIC of BAI | MIC of 1⁄2 BAI + COL |
MIC fold change | MIC of EDTA | MIC of 1⁄2 EDTA + COL |
MIC fold change | MIC of 1⁄2 BAI + 1⁄2 EDTA |
MIC fold change | |||||||
JS | – | – | 1/2 | 2500 | 1/2 | 1 | – | 125 | 1/32 | 16 | – | 1/256 | 128 | – |
SR01 | chicken | Table S1 | 32 | 2500 | 4 | 8 | None | 125 | 2 | 16 | Reverse | 1/8 | 256 | Reverse |
SR02 | chicken | Table S1 | 4 | 2500 | 1/4 | 16 | Reverse | 250 | 1/8 | 32 | Reverse | 1/256 | 1024 | Reverse |
SR03 | chicken | Table S1 | 32 | 2500 | 8 | 4 | None | 250 | 1 | 32 | Reverse | 1/16 | 512 | Reverse |
SR04 | chicken | Table S1 | 32 | 2500 | 2 | 16 | Reverse | 125 | 1/2 | 64 | Reverse | 1/32 | 1024 | Reverse |
SR05 | chicken | Table S1 | 4 | 2500 | 1 | 4 | Reverse | 125 | 1/4 | 16 | Reverse | 1/32 | 128 | Reverse |
SR06 | chicken | Unknown | 16 | 2500 | 1/2 | 32 | Reverse | 125 | 4 | 4 | None | 1/32 | 512 | Reverse |
SR07 | chicken | Unknown | 16 | 2500 | 2 | 8 | Reverse | 125 | 2 | 8 | Reverse | 1/8 | 128 | Reverse |
SR08 | chicken | Unknown | 8 | 2500 | 1 | 8 | Reverse | 125 | 1 | 8 | Reverse | 1/32 | 256 | Reverse |
SR09 | chicken | Table S1 | 32 | 2500 | 2 | 16 | Reverse | 125 | 2 | 16 | Reverse | 1/128 | 4096 | Reverse |
SR10 | chicken | Table S1 | 32 | 2500 | 1 | 32 | Reverse | 125 | 1 | 32 | Reverse | 1/512 | 16384 | Reverse |
SR11 | chicken | Unknown | 32 | 2500 | 8 | 4 | None | 125 | 4 | 8 | None | 1/4 | 128 | Reverse |
SR12 | chicken | Unknown | 64 | 2500 | 4 | 16 | None | 125 | 4 | 16 | None | 1/8 | 512 | Reverse |
SR13 | chicken | mcr-1 | 16 | 2500 | 2 | 8 | Reverse | 125 | 1 | 16 | Reverse | 1/16 | 256 | Reverse |
SR14 | chicken | mcr-1 | 32 | 2500 | 4 | 8 | None | 125 | 2 | 16 | Reverse | 1/8 | 256 | Reverse |
SR15 | human | mcr-1 | 64 | 2500 | 1 | 64 | Reverse | 125 | 4 | 16 | None | 1/4 | 256 | Reverse |
SR16 | human | Unknown | 32 | 2500 | 4 | 8 | None | 125 | 1/2 | 64 | Reverse | 1/64 | 2048 | Reverse |
SF01 | human | – | 1 | 2500 | 1/4 | 4 | – | 500 | 1/128 | 128 | – | 1/1024 | 1024 | – |
SF02 | human | – | 1/2 | 2500 | 1/4 | 2 | – | 250 | 1/2 | 1 | – | 1/8192 | 4096 | – |
SF03 | chicken | – | 1/8 | 2500 | 1/32 | 4 | – | 125 | 1/128 | 16 | – | 1/2048 | 256 | – |
SF04 | chicken | – | 1 | 2500 | 1/4 | 4 | – | 250 | 1/4 | 4 | – | 1/256 | 256 | – |
Note: The “−” means that the strain is sensitive to colistin; BAI, baicalin. COL, colistin.