Figure 3.

T3 and glucose enhance β cell proliferation. Human islets (A), Mouse islets (B) or Ins-1 cells (C) were dispersed and incubated at the indicated glucose or T3 concentrations in RPMI containing 10% resin-stripped serum. After 48 h, cells were fixed and immunolabeled for Ki67 and insulin. Presented are the percent of Ki67-positive and Insulin-positive cells. Data are the means ± SEM of at least three independent experiments. ∗P < 0.05; ∗∗P < 001; ∗∗∗P < 005; ∗∗∗∗P < 001 by two-way ANOVA.