Table 4.
Factors associated with 90-day mortality in mechanically ventilated adults with COVID-19.
Univariable HR [95%CI] | p-Value | Multivariable HR [95%CI] | p-Value | ||
---|---|---|---|---|---|
Age, per 10 years | 1.49 [1.40–1.58] | <0.001 | 1.47 [1.37–1.58] | <0.001 | |
Body mass index >30 kg.m−2 | 0.82 [0.72–0.94] | 0.004 | 0.94 [0.81–1.09] | 0.39 | |
Diabetes | 1.50 [1.32–1.70] | <0.001 | 1.30 [1.13–1.50] | <0.001 | |
Immunodeficiency | 1.74 [1.47–2.06] | <0.001 | 1.60 [1.33–1.96] | <0.001 | |
Time between first symptoms and ICU admission, per day | 0.96 [0.95–0.87] | <0.001 | 0.96 [0.95–0.98] | <0.001 | |
Non-respiratory SOFA score at intubation, per one point | 1.10 [1.07–1.13] | <0.001 | 1.09 [1.06–1.12] | <0.001 | |
PaO2/FiO2 at intubation, per 10 mmHg | 0.99 [0.98–0.998] | 0.02 | 0.98 [0.98–0.99] | 0.003 | |
At least one episode of VAP | 1.38 [1.20–1.58] | <0.001 | 1.34 [1.16–1.55] | <0.001 |