TABLE 1.
Baseline characteristics of HBV-ACLF patients.
| All patients (n = 200) |
Surviving patients (n = 146) |
Non-surviving patients (n = 54) | P | |
| Male [n (%)] | 174 (87.0) | 127 (86.9) | 47 (87.0) | 0.824 |
| Age (years) | 48.25 ± 11.69 | 46.99 ± 11.21 | 51.67 ± 12.36 | 0.012 |
| Expense (USD) | 10922.65 (6759.39–17669.28) | 11334.59 (6838.99–17459.69) | 9705.85 (6255.59–18040.91) | 0.595 |
| WBC (109/L) | 6.590 (5.158–8.368) | 6.550 (5.202–8.238) | 6.695 (4.820–9.015) | 0.453 |
| PLT (109/L) | 110.50 (79.00–140.75) | 115.00 (86.00–145.00) | 86.50 (51.00–134.50) | 0.008 |
| INR | 1.96 (1.70–2.52) | 1.90 (1.69–2.36) | 2.09 (1.76–2.84) | 0.018 |
| PT (s) | 21.95 (19.20–27.93) | 21.15 (18.98–25.73) | 23.80 (19.98–31.48) | 0.019 |
| Hb (g/L) | 124.50 (110.00–137.75) | 125.00 (113.00–140.00) | 121.50 (103.75–133.75) | 0.134 |
| Albumin (g/L) | 31.47 ± 4.52 | 32.08 ± 4.55 | 29.81 ± 4.01 | 0.001 |
| Creatinine (μmol/L) | 66.45 (57.35–81.15) | 64.70 (57.08–78.25) | 72.65 (58.63–92.60) | 0.048 |
| BUN (mmol/L) | 4.00 (2.70–5.58) | 3.75 (2.60–5.20) | 5.15 (3.32–5.52) | 0.001 |
| ALT (μ/L) | 364.00 (127.50–887.00) | 291.45 (128.70–716.13) | 409.50 (125.50–950.75) | 0.373 |
| AST (μ/L) | 245.50 (131.55–581.75) | 232.00 (123.75–608.75) | 263.15 (162.25–554.00) | 0.391 |
| Bilirubin (μmol/L) | 315.90 ± 135.73 | 302.49 ± 123.30 | 352.15 ± 160.47 | 0.021 |
| TC (mg/dL) | 97.81 (78.19–118.69) | 104.58 (80.70–124.00) | 84.28 (69.59–101.68) | <0.001 |
| HDL-C (mg/dL) | 8.12 (5.90–10.82) | 8.51 (6.57–12.47) | 6.57 (4.64–8.51) | <0.001 |
| CTPs | 11.00 (10.00–12.00) | 11.00 (10.00–12.00) | 12.00 (11.00–13.00) | <0.001 |
| MELDs | 22.59 (19.57–26.36) | 21.61 (18.85–25.49) | 24.45 (21.73–28.50) | <0.001 |
| COSSH-ACLF IIs | 6.97 (6.41–7.77) | 6.73 (6.30–7.25) | 7.72 (6.99–8.65) | <0.001 |
P-value < 0.05 was considered significant and was indicated in bold. ACLF, acute on chronic liver failure; HBV, hepatitis B Virus; USD, dollar; WBC, white blood cell count; PLT, platelet; INR, international normalized ratio; PT, prothrombin time; Hb, hemoglobin; BUN, blood urea nitrogen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; CTPs, child-turcotte-pugh score; MELDs, model for end-stage liver disease score; COSSH-ACLF IIs, Chinese Group on the Study of Severe Hepatitis B-ACLF II score.