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. 2022 Nov 25;9:1001411. doi: 10.3389/fmed.2022.1001411

TABLE 3.

Clinical data according to HDL-C levels.

Low HDL-C group (n = 21) High HDL-C group (n = 179) P
Male [n (%)] 18 (85.7) 156 (87.2) 1.000
Age (years) 57.00 ± 13.40 47.22 ± 11.07 <0.001
Expense (USD) 9479.7 (5448.1–17680.8) 11238.2 (6761.9–17756.1) 0.482
WBC (109/L) 6.67 (5.25–8.53) 5.53 (4.40–7.50) 0.045
PLT (109/L) 81.00 (48.00–121.50) 114.00 (82.00–144.00) 0.012
INR 2.12 (1.64–2.68) 1.94 (1.71–2.52) 0.634
PT (s) 23.60 (18.45–28.45) 21.80 (19.20–27.85) 0.785
Hb (g/L) 126.00 (108.00–139.00) 123.00 (110.00–138.00) 0.757
Albumin (g/L) 30.92 ± 2.78 31.53 ± 4.68 0.558
Creatinine (μmol/L) 74.20 (60.80–97.05) 64.90 (57.20–79.80) 0.110
BUN (mmol/L) 5.40 (3.60–8.35) 4.00 (2.60–5.45) 0.007
ALT (μ/L) 383.00 (126.00–947.00) 253.00 (111.35–625.35) 0.291
AST (μ/L) 198.00 (142.50–351.25) 249.00 (131.40–629.00) 0.511
Bilirubin (μmol/L) 382.77 ± 137.96 308.05 ± 133.68 0.017
TC (mg/dL) 85.43 (68.23–102.06) 100.90 (78.48–121.01) 0.018
CTPs 12.00 (10.50–12.00) 11.00 (10.00–12.00) 0.046
MELDs 25.04 (22.01–28.72) 22.21 (19.55–26.23) 0.021
COSSH-ACLF IIs 7.63 (7.08–8.64) 6.88 (6.36–7.69) 0.001
28-days mortality [n (%)] 18 (85.71) 36 (20.11) <0.001

P-value < 0.05 was considered significant and was indicated in bold. ACLF, acute on chronic liver failure; HBV, hepatitis B Virus; USD, dollar; WBC, white blood cell count; PLT, platelet; INR, international normalized ratio; PT, prothrombin time; Hb, hemoglobin; BUN, blood urea nitrogen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; CTPs, child-turcotte-pugh score; MELDs, model for end-stage liver disease score; COSSH-ACLF IIs, Chinese Group on the Study of Severe Hepatitis B-ACLF II score.