Table 1.

Samples of literature-sourced half-lives to compare with our SARS-CoV-2 two-dose mRNA-vaccine values.

Parameter	Definition	Fitted value (${\text{d}}^{-1}$)	Equivalent half life	Half life value sourced from the literature
${\gamma }_A$	IgG degradation rate	0.042 (mRNA-1273), 0.043 (BNT162b2)	$\sim$16 days	36 days (IgG) $†$29, 21 days (IgG) $†$30, 20.4 days (NAb) $†$31, 68.8 days (anti-S titres)32
${\gamma }_V$	Antigen presenting cell decay rate	0.07	10 days	10 days (mice)$\ast$ $†$33
${\gamma }_F$	IFN-$\gamma$ clearance rate	201.24	5 min	30 min (human)34, less than 3 min (mice)35, 40 min (mice)36
${\gamma }_I$	Interleukin clearance	0.027	25.7 days	15.5 h (IL-6, mice)37, 2.5-5 h (IL-15, human)38, 5 h (IL-8, human)39
${\gamma }_B$	Plasma B cell degradation rate	0.071	9.8 days	11.6 days (human)$†$40, 7-8 weeks (mice)41, 18 days (human)42

Literature sourced values are not necessarily SARS-CoV-2-specific, rather are listed here to demonstrate that the model-determined values are correct to within an order of magnitude of other values found in the literature. $\ast$ This value is not a half life, but is the total observed time of translation. $†$ These values are SARS-CoV-2 specific.