TABLE 2.
Correlations between bone scintigraphy quantitative measures and biological bone turnover markers of disease activity and scoliosis angle.
Spearman correlations (ρ, CI, p-value) | SUVmax | SUVmean | SBS | SBS_SUVmax | SBS_SUVmean |
FGF-23 | (0.28, –0.69–0.89, 0.585) | (0.29, –0.68–0.89, 0.581) | (0.81, –0.02–0.98, 0.053) | (0.91, 0.40–0.99, 0.010) | (0.91, 0.36–0.99, 0.013) |
ALP | (0.01, –0.81–0.81, 0.994) | (0.01, –0.81–0.81, 0.997) | (0.79, –0.05–0.98, 0.060) | (0.82, 0.25–0.99, 0.020) | (0.88, 0.26–0.99, 0.019) |
P1NP | (0.04, –0.73–0.77, 0.928) | (0.06, –0.73–0.77, 0.901) | (0.69, –0.14–0.95, 0.089) | (0.78, 0.06–0.97, 0.039) | (0.78, 0.07–0.97, 0.028) |
CTX | (0.13, –0.85–0.91, 0.837) | (0.18, –0.84–0.92, 0.772) | (0.96, 0.50– 0.99, 0.010) | (0.99, 0.83–0.99, 0.002) | (0.99, 0.85–0.99, 0.001) |
Scoliosis angle | (0.33, –0.56–0.87, 0.472) | (0.36, –0.52–0.88, 0.432) | (0.58, –0.31–0.93, 0.168) | (0.62, –0.25–0.94, 0.137) | (0.63, –0.24–0.94, 0.133) |
CI, Confidence interval; SUV, Standard uptake value; SUVmax, maxium Standard Uptake Value; SUVmean, mean Standard Uptake Value; SBS, Skeletal Burden Score; SBS_SUVmax, SBS score multiplied by SUVmax; SBS_SUVmean, SBS score multiplied by SUVmean; FGF-23, Fibroblast growth factor 23; ALP, Alkaline phosphatase; P1NP, Procollagen 1 intact N-terminal propeptide; CTX, C-terminal telopeptide.