Figure 5.

Relative expression levels of (A) interleukin 1β (IL-1β), (B) interleukin 6 (IL-6), (C) leukemia inhibitory factor (Lif), (D) vascular endothelial growth factor (Vegf), (E) Janus kinase 2 (Jak2), (F) signal transducer and activator of transcription 3 (Stat3), and (G) matrix metalloproteinase 9 (Mmp-9), mRNA expression in the different groups. The mRNA levels of genes were analyzed with qPCR (the reference gene was beta-2 microglobulin). The histogram demonstrates that the expression of genes in the human chorionic gonadotropin (HCG)-producing peripheral blood mononuclear cells (PBMCs) group was significantly higher than in the other groups. Values are presented as mean±standard deviation. EID, embryo implantation dysfunction; EID+recombinant vector, EID with HCG-producing PBMC; qPCR, quantitative real-time polymerase chain reaction. ^a)p≤0.02; ^b)p≤0.003; paired t-test.