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. 2022 Nov 25;13:1055304. doi: 10.3389/fimmu.2022.1055304

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Copyright © 2022 Zhang, Li, Li, Zhou, Chen, Liu, Wang, Jiang, Wang, Liu, Zhao and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TME differences and underlying immunotherapy of different subtypes of bladder cancer: (A) Division of bladder cancer into three subtypes; (B, C) The t-SNE and PCA analysis of different subtypes; (D) Sankey diagram of interrelationship between three subtypes and high- and low-risks; (E) Heat map of immunocyte-related analysis of subtypes; (F) Differences in immune microenvironment scores of different subtypes; (G) Histogram of immune checkpoint expression differences between subtypes; (H) OS analysis curves of patients with different subtypes of bladder cancer; (I) cluster 2 drug sensitivity analysis. **p < 0.01, *p < 0.05.