TABLE 1.

Propofol inhibits tumors by regulating miRNAs/lncRNAs.

MiRNA/LncRNA	Regulation	Cancer types	Targets	Mechanism	Ref
MiRNA	Downregulation	Bladder cancer	miR-10b	miR-10b/HOXD10	Qi et al. (2019a)
		Lung cancer	miR-21-5p	miR-21-5p/MAPK10	Wu et al. (2020)
		Lung cancer	miR-372	Suppressed Wnt/β-catenin and mTOR signaling pathways	Sun and Gao, (2018)
		Breast cancer	miR-24	Upregulating p27 and cleaved caspase-3 expression	Yu et al. (2018)
		Breast cancer	miR-21	Suppressed Wnt/β-catenin and PI3K/AKT signaling pathways	Du et al. (2019)
	Upregulation	Gastric cancer	miR-195-5p	miR-195-5p/snail	Liu et al. (2020)
		Renal cancer	miR-363	Reduced the expression of Snail1	Shi et al. (2021)
		Lung cancer	miR-1284	Reduced the expression of FOXM1	Liu and Liu, (2018)
		Papillary thyroid carcinoma	miR-122	Reduced the expression of MMP2 and MMP9	Li et al. (2020a)
		Colorectal cancer	miR-124-3p	Reduced the expression of AKT3	Li et al. (2020b)
		Liver cancer	miR-219-5p	Suppression of GPC3-mediated Wnt/β-catenin signaling activation	Gong et al. (2019)
		Thyroid cancer	miR-141-3p	Suppressing SHH and PI3K/AKT signaling pathways via the miR-141-3p/BRD4 axis	Zhang et al. (2021a)
LncRNA		Ovarian cancer	lncRNA HOST2	Suppressing JAK2/STAT3 signaling pathway	Shen et al. (2021)
		Liver cancer	lncRNA CASC9	Suppressing Akt/mTOR signaling pathway	Chang et al. (2022)
		Colon cancer	lncRNA HOTAIR	Activating WIF-1 and Suppressing Wnt pathway	Zhang et al. (2020a)
		Glioma	lncRNA GAS5	Increasing the expression of P21, decreasing the expression of c-myc and GSTM3	Cheng et al. (2022)
		Oral squamous cell carcinoma	lncRNA GAS5	FoxO1-GAS5-miR-1297-GSK3b axis	Gao et al. (2019)
	Interactions between lncRNA and miRNA	Colorectal cancer	lncRNA HOXA11-AS	lncRNA HOXA11-AS/miR-let-7i/ABCC10	Ren and Zhang, (2020)
		Liver cancer	lncRNA HOXA11-AS	lncRNA HOXA11-AS/miR-4458	Song et al. (2020)
		Liver cancer	LncRNA NORAD	lncRNA NORAD/miR-556-3p/MIEN1	Liu et al. (2021a)
		Esophageal cancer	lncRNA TMPO-AS1	lncRNA TMPO-AS1/miR-498	Gao et al. (2020)